What is the name of the irreversible inhibitor (drug) used as an example in the lecture?

Answers

Answer 1

Diisopropylfluorophosphate (DPF) is the irreversible inhibitor (drug) used as an example in the lecture. the its an enzyme hydrolyses the pheophrous- Florine bond, but the phosphate remains bound to serine in the active site and deactivating it.

Irreversible inhibitor are contently /non contently bound to the specific enzyme and slow down the enzyme. invisible hibitors are 3 types such as group specific reagents , reactive substrate analogs also known as affinity label and inhibitor.

There are some examples of irreversible inhibitors -compound diisopropylphosphofluoridate (DIPF), nerve gases ,acetylcholinesterase ,and preventing transmission of impulse. Penicillin irreversibly inhibits the enzyme transpeptidase by reacting with transpeptidase.

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Related Questions

Soil is BIOLOGICALLY weathered with the help of which of these?

A. temperature changes

B. water and wind

C. tree roots, lichens, and other living organisms

Answers

Answer:

C

Explanation:

The key word here is "biologically", thus involving living things.

Temperature changes and water/wind are not living organisms that impact the weathering of soil. However, tree roots and lichens are living and break the soil down for nutrients.

While on the beagle, darwin's observations suggested that ________ is (are) a better predictor of relationships among organisms than ________

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While on the beagle, darwin's observations suggested that geographic proximitys (are) a better predictor of relationships among organisms than similarity of environment.

Darwin spent most of his time on land during the Beagle's five-year trip, gathering thousands of samples of fossils and living plants and animals. Many of Darwin's discoveries suggested that geographic proximity rather than environmental similarity is a better predictor of relationships between organisms.

For instance, the South American fossils Darwin discovered were also uniquely South American in that they resembled the living plants and animals of that continent, although clearly belonging to a different species from the ones that are alive today.

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Which part of the nephron is responsible for the greatest possible increase in urine concentration?

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Bowman's capsule collecting duct loop of Henle is the part of the nephron is responsible for the greatest possible increase in urine concentration.

Maximum concentration occurs at the bottom of the loop. The ascending limb of the nephron loop is impermeable to water, but Na + and Cl – are pumped out into the surrounding fluids by active transport.

The production of concentrated urine involves complex interactions among the medullary nephron segments [5;6] and vasculature. In outer medulla, the thick ascending limbs of the loops of Henle actively reabsorb NaCl.

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What percent of blood from digestion passes through the liver before returning to the heart?

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100% of the blood from digestion passes through the liver before returning to the heart.

The hepatic portal system is the venous system that returns blood from the digestive tract and spleen to the liver. The raw nutrients in the blood are processed in the liver before the blood returns to the heart.

The hepatic portal vein supplies 75% of the blood to the liver, while the hepatic arteries supply the remaining 25%.

In the liver, carbohydrates and amino acids can be stored or used to synthesize new proteins and carbohydrates.

The liver also extracts vitamins and cofactors from the blood for storage, as well as filters any toxins that may have been absorbed along with the food.

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What kind of cell is involved in the process of scarring?

Answers

Scars are comprised mainly of collagen, a fibrous protein secreted by a type of cell found in the skin called a fibroblast. Collagen is one of the main components of the extracellular matrix — a three-dimensional web that supports and stabilizes the cells in the skin.

Answer:

EPF Cells (Engrailed-Positive Fibroblast Cells)

Explanation:

Researchers found evidence that EPF cells are clearly responsible for the vast majority of scarring.

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During the measurement of blood pressure with a sphygmomanometer, diastolic blood pressure is recorded when:_____.

Answers

During the measurement of blood pressure with a sphygmomanometer, diastolic blood pressure is recorded when you no longer hear the beating sounds. This is your diastolic pressure.

While measuring the diastolic blood pressure watch the mercury level in the sphygmomanometer.

Note the sphygmomanometer reading (the number the mercury has reached) when the pulse reappears. Record this as the systolic pressure.

Deflate the cuff further until the pulse disappears. Record this reading as the diastolic pressure.

Blood pressure is measured in units of millimeters of mercury (mmHg). If someone has a reading of 132/88 mmHg, they have a systolic blood pressure of 132 mmHg and a diastolic blood pressure of 88 mmHg.

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Organisms in the same ecosystem are all _______. a. interrogative b. interdependent c. intermediate d. interceptive please select the best answer from the choices provided a b c d

Answers

Option (B) Interdependent is the correct answer.

How do organisms live in an ecosystem?

An ecosystem comprises two components ie. living and non-living. Living components include all the organisms such as animals, humans, plants, etc., and nonliving components include soil, air, water, etc. All the organisms which live in the same ecosystem are interdependent, as well as dependent on nonliving components too. This is called interdependence.

They are dependent on each other for food, shelter, pollination, seed dispersal, etc.

The food chains and food webs are the most important example of interdependence shown by organisms living in an ecosystem.

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Answer:

B

Explanation:

Edge 2022

Select all the correct answers. which three statements provide reasons that scientists are considering renewable sources of energy?

Answers

The option 1, option 3, and option 4 is correct.

The three statement related to the renewable sources of energy should be clean & non-pollutting, conventional resources, and available in nature.

What is renewable sources of energy?

Renewable energy comes from natural sources that replace themselves more quickly than they are used up. Examples of such sources that are continuously replenished are the sun and the wind. There are many different types of renewable energy available to us.

The most popular renewable energy sources currently are:

Solar energy.Wind energy.Hydro energy.Tidal energy.Geothermal energy.Biomass energy.

Therefore, based on this, we can conclude that the option 1, option 3, and option 4 is correct.

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The complete question is -

Select all the correct answers.

Which three statements provide reasons that scientists are considering renewable sources of energy?

1. Most renewable resources are clean and nonpolluting.

2. Renewable resources can be replenished.

3. Renewable resources are conventional resources.

4. Most renewable resources are easily available in nature.

5. All renewable resources are cost effective.

What position should the foot/ankle be in when observing for structural deformities?

Answers

The position that the foot/ankle should be in when observing for structural deformities is the Subtalar joint neutral position.

What is the Subtalar joint neutral position?

One of the most intricate joints for supporting weight is the subtalar joint (STJ). Small biomechanical or anatomical factors can frequently have a big therapeutic impact.

The midtarsal joints and the forefoot's movements are controlled by the STJ, which converts the rotatory forces of the lower extremities.

Before creating a biomechanical functional orthosis, doctors frequently take a cast impression of a patient's foot in the subtalar neutral position.

However, numerous tests have demonstrated that no single approach for determining STJ neutrality is accurate and repeatable.

The position where the concave and convex surfaces are perfectly congruous is known as the joint's neutral position.

Therefore, the position that the foot/ankle should be in when observing for structural deformities is the Subtalar joint neutral position.

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The lithosphere is broken into approximately ____________ dozen smaller sections called lithospheric plates that are in constant motion.

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The lithosphere is broken into approximately Two Dozen dozen smaller sections called lithospheric plates that are in constant motion.

What is earth's lithosphere?

The most well-known feature associated with the Earth's lithosphere is tectonic activity. Tectonic activity describes the interaction of huge plates of lithosphere called tectonic plates.

The lithosphere is divided into tectonic plates including the North American, Caribbean, South American, Scottish, Antarctic, Eurasian, Arabian, African, Indian, Philippine, Australian, Pacific, Juan de Fuca, Coconut, and Nazca plates.

Most tectonic activity takes place at the boundaries of these plates, where they can collide, tear apart, or slide against each other. The movement of tectonic plates is made possible by thermal energy (heat) from the mantle part of the lithosphere. Thermal energy makes the rocks of the lithosphere more flexible.

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Why is onpg used as the substrate for the β-galactosidase assay rather than lactose?

Answers

Answer:

Explanation:

Unlike lactose, the substrate O-nitrophenyl-beta-D-galactopyranoside (ONPG) is capable of penetrating the bacterial cell without the presence of permease. In the broth method of testing, the organism is taken from a medium containing a high concentration of lactose and is inoculated into the ONPG Broth.

What is the role of alveoli in respiration

Answers

Answer:

What is the role of alveoli in respiration ⇔ Alveoli are the place where the exchange of gases takes place. The outer part of alveoli has blood vessels. These vessels are carrying Co2 rich blood to exchange at the alveoli. The O2 from the alveoli is diffused into the blood while co2 is sent into the lungs. That O2 rich blood is then carried to heart to pump it to the whole body. and this process continues. The alveoli are where the lungs and the blood exchange oxygen and carbon dioxide during the process of breathing in and breathing out.

Explanation:

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The decrease in reproductive function, resulting in a decrease in testosterone and inhibin secretion, is called?

Answers

The decrease in reproductive function, resulting in a decrease in testosterone and inhibin secretion, is called male Climacteric or andropause.

Inhibin is a protein secreted by the Sertoli cells in men and by the granulosa cells in women. It inhibits the synthesis and release of the follicle-stimulating hormone in the pituitary gland and reduces the hypothalamic LH releasing hormone content. The testes also produce inhibin B and anti-Müllerian hormone from Sertoli cells, and insulin-like factor 3 and estradiol from the Leydig cells..

The maintenance of inhibin production by the testis requires the support of pituitary hormones, presumably FSH, while seminiferous tubule fluid production requires testosterone, presumably through LH stimulation of Leydig cells.

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According to freud’s view of personality structure, the "executive" system, the _______, seeks to gratify the impulses of the __________ in more acceptable ways

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According to Freud's view of personality structure the executive system the ego seeks to gratify the impulses of the id in more acceptable ways.

According to Freud personality structure theory - " mind is divided into three components id, ego and superego. The interactions and conflicts among the components create personality. The ego which operates the reality principle which satisfying the id's desire in ways that will realistically bring pleasure rather then the pain.

He believes that the personality is a result from conflict arsing from the interaction among the minds's three systems. Behavior and personality were derived from the constant and unique interaction of conflicting psychological forces that operates three level of awareness that is - precocious, conscious, unconscious.

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A mutation in which one nucleotide in the dna sequence is substituted for another nucleotide is referred to as a ________ mutation

Answers

the answer is a point mutation

Why do you think the value of pk1 increases for alanine when it's part of an oligopeptide compared to free alanine?

Answers

The value of pk1 increases for Alanine when it's part of an oligopeptide compared to free Alanine due to decreased electrostatic interaction between the amino group and carboxylic group which lowers the strength of acidic group i.e. carboxylic group.

The amino acids are amphoteric in nature and have two or three pK values, depending on their side chains. pKa1 is the α-carboxyl group, pKa2 is the α-ammonium ion, pKa3 is the side chain group (if applicable).

Electrostatic interaction between the carboxylate anion and the protonated amino group of the Alanine zwitterion favorably affects the ionization of the carboxyl group. This favorable interaction decreases as the length of the poly-Ala increases, resulting in an increase in pK1.

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One advantage of branched sugar polymers is the availability of more ends for chemical reaction.

a. true
b. false

Answers

The one advantage of branched sugar polymers is the availability of more ends for chemical reactions. So, the statement is true.

What are branched sugar polymers?

Polysaccharides are simply the monomers of thousands of monosaccharides units. The kind of polysaccharide formed will be based on the kind of monosaccharide units involved.

The branching of monomers helps in the formation of polysaccharides. Branching of glucose monomers in the formation of different polysaccharides. These are starch and cellulose present in plants and glycogen in animals.

These kinds of polysaccharides are made of a lot of monomers and that is caused by the branching. This kind of branching can also help in the addition of more monomeric units to make a longer polysaccharide chain.

Therefore, an advantage of branched sugar polymers is the availability of more ends for chemical reactions.

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Administration of testosterone should lead to male mating behavior in an animal only if...

Choices:
The requisite sexually dimorphic nuclei are sufficiently masculinized


There are high levels of estrogen in the brain


There are low levels of estrogen in the brain


The requisite sexually dimorphic nuclei are sufficiently defeminized

Answers

Administration of testosterone should lead to male mating behavior in an animal only if The requisite sexually dimorphic nuclei are sufficiently masculinized.

The main sex hormone and anabolic steroid in guys is testosterone. In humans, testosterone is essential for the growth of the testes and prostate, as well as for the promotion of secondary sexual traits including increased bone and muscle mass and the development of body hair. Through territorial aggression, wooing rituals, and mate-guarding behavior, high testosterone levels have been found to improve mating effort.

The preoptic area of the hypothalamus, where the sexually dimorphic nucleus -POA is situated, regulates male sexual behavior. Snake, reptile, avian, rodent, ungulate, and primate male-typical copulatory activity is reduced by large lesions in the preoptic region.

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What enzyme allows h ions to diffuse back across the membrane down their concentration gradient? this process releases energy, what is this energy used for?

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What enzyme allows h ions to diffuse back across the membrane down their concentration gradient? this process releases energy, what is this energy used for? ATP Synthase. This proton gradient (gradient of H+) flowing through the membrane enzyme complex ATP synthetase is the direct energy source for producing ATP.

What is ATP synthase?

Adenosine diphosphate (ADP) and inorganic phosphate are used to create the energy storage molecule adenosine triphosphate (ATP) by a protein called ATP synthase . It is categorized as a ligase since it modifies ADP by forming a P-O link (phosphodiester bond). A molecular device called ATP synthase. The overall reaction that ATP synthase catalyzes is:

ATP + H2O + 2H+in ADP + Pi + 2H+out

Energy-wise, the production of ATP from ADP and Pi is undesirable, and the process would typically go the other way. A proton (H+) concentration gradient across the inner mitochondrial membrane in eukaryotes or the plasma membrane in bacteria drives this reaction forward by coupling ATP synthesis during cellular respiration to the gradient.

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When sympathetic activation occurs, there is increased activity in the cardiovascular and respiratory centers of the ________.

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When sympathetic activation occurs, there is increased activity in the cardiovascular and respiratory centers of the

Pons and medulla oblongata

What is sympathetic activation?

One of the three divisions of the autonomic nervous system, along with the parasympathetic and enteric nervous systems, is the sympathetic nervous system (SANS or SYNS). The enteric nervous system is occasionally regarded as a component of the autonomic nervous system and other times as a separate entity.

The autonomic nerve system controls the body's automatic movements. The major function of the sympathetic nervous system is to activate the body's fight-or-flight response. However, in order to maintain homeostasis, it is continually active. The parasympathetic neural system, which drives the body to "eat and breed" before (then) "rest-and-digest," is said to be antagonistic to the sympathetic nervous system.

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A scientist discovers an unknown multicellular organism that filters microorganisms from its marine habitat for food and reproduces sexually.

Which kingdom does the organism most likely belong to?


Animalia


Fungi


Protista


Plantae

Answers

Animalia is a multicellular organism that filters microorganisms from its marine habitat for food and reproduces sexually.

Kingdom Animalia:

All kinds of animals are present in Kingdom Animalia. This kingdom's members are all multicellular and comprise eukaryotic cells. They consume other species because they are heterotrophic. Invertebrates like snails and sea anemones and vertebrates like humans and dolphins make up the diversified kingdom of Animalia. They come in all sizes, from blue whales that are 100 feet long to microscopic rotifers.

They have muscle cells, which give them the capacity to relax and contract different body sections. It is sexual to reproduce. However, lesser forms also engage in asexual reproduction. The zygote develops into a multicellular embryo during development. To carry out aerobic respiration, they need oxygen. Animal Phyla- Biologists recognize about 36 separate phyla within the Kingdom Animalia.

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The _________ is a temporary organ that is the site of exchange of oxygen, nutrients, and wastes between the mother and fetus, and the ________ connects the placenta to the embryo

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"The placenta is a temporary organ that is the site of exchange of oxygen, nutrients, and wastes between the mother and fetus, and the umbilical cord connects the placenta to the embryo."

The term "placenta" refers to the transient vascular organ that is present in mammals and holds the baby to the mother's uterus during pregnancy. A developing newborn receives oxygen and nutrients from this structure. It also cleans the baby's blood of waste materials. Only mammals have a placenta.

The transmission of materials is facilitated by the umbilical cord, which joins the fetus and placenta. The network of blood veins in the uterine wall connects the mother to the placenta. The umbilical cord has a vein and two arteries. It transports waste materials away from the fetus and supplies it with oxygen and nutrition.

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In the context of nutritional status assessment, height, body weight, and body composition are frequently used?

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Dietary assessors in the context of nutritional status assessment ,height , body weight and body composition are frequently used.It is important not only in study of associations between diet and health related outcomes but also for nutritional status of patients in clinical settings.

Anthropometry is the measurement of physical dimension such as height , body weight and composition of human body to provide information related to individuals nutritional status.

It involves the collection of information on food and drink consumed over specific time that is coded and processed to compute intakes of energy  and nutrients or others dietary constituents using food composition tables.

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Features that result from wave deposition include

Select one:

a.
groins


b.
barrier islands


c.
sea walls


d.
sea stacks

Answers

Answer:

b.barrier islands

Explanation:

Barbara mcclintock examined the mechanism for the appearance of purple spots in the kernels of yellow and white corn. She attributed the spots to?

Answers

Barbara Mcclintock examined the mechanism for the appearance of purple spots in the kernels of yellow and white corn. She attributed the spots to transposable elements(TE)  or jumping genes.

McClintock studied the so-called Ac/Ds system in maize, which she learned about by carrying out conventional genetic breeding experiments with a peculiar phenotype. Through these tests, McClintock discovered that breakage happened at particular locations on the maize chromosomes.

She did, in fact, find the first transposable element (TE) at the aptly termed "dissociation" location of chromosome breakage (Ds). McClintock initially observed that the movements of Ds are controlled by an autonomous element called "activator" (Ac), which may also promote its own transposition. She later discovered that some TEs could "jump" autonomously.

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To participate in a designated driver program and be provided with complimentary nonalcoholic drinks you must meet certain criteria, which are?

Answers

To participate in a designated driver program and be provided with complimentary nonalcoholic drinks you must meet certain criteria, which are a part of a group of two or more, identify yourself as the designated driver, and be at least 21 years old.

A non-alcoholic drink, often known as a temperance drink, is an alcoholic drink that is created without alcohol, or with the alcohol eliminated or reduced to virtually nothing.

Non-alcoholic beer has extremely little or no alcohol. Non-alcoholic beers sold in the United States are allowed to contain up to 0.5 percent alcohol by volume (ABV), yet several brands claim to offer 0% ABV.

Ethanol distillation is used to separate alcoholic beverages into non-alcoholic beverages and spirits. Similar non-alcoholic drinks are authorized in places where alcohol is prohibited.

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You mate a female m1 fly to a male m3 fly. if these two flies have recessive mutations in the same gene, what percentage of their offspring will have sleep defects?

Answers

There is only 50 %  chance that offspring have a sleep defects. The simplest test to distinguished between the two possibilities is the complementation test.

When two recessive organism are crossed then mutation are in the same gene , both copies of gene will be mutant in F1 offspring and they will exhibit the same phenotype as their parents.

The exact mutation may be different but both allele of single gene are mutant and the recessive phenotype will be  observed. If two mutants have homozygous recessive mutant alleles for two different genes. Complementations is occurs when two strains of an organisms with different homozygous recessive mutations that produce the same mutant phenotype.

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Which statement BEST supports the choice made in Part A? A The diagram shows four daughter gametes that have exchanged genetic information between chromatids. B The diagram shows four unique gametes that are the result of receiving one random allele from each parent. C The diagram shows four unique gametes that are the result of two chromosomes separating in different ways. D The diagram shows four daughter gametes that incorrectly contain fewer chromosomes than the parent cells.

Answers

A statement which best supports the choice made in Part A (independent assortment) is: C. The diagram shows four unique gametes that are the result of two chromosomes separating in different ways.

Mendel's law of independent assortment.

Mendel's law of independent assortment is a theory which states that the alleles of two or more different genes are sorted into unique gametes that are independent of each another.

This ultimately implies that, the allele that is typically being received by a gamete for one gene doesn't influence or affect the type of allele that is received for another gene.

Based on the biological process (independent assortment) shown in the image attached below for part A, we can infer and logically deduce that a statement which best supports the choice made is that he diagram shows four unique gametes that are the result of two chromosomes separating in different ways.

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What is one benefit if using SI units

Answers

ANSWER: the comparison of data all over the world can be done quickly

The major disadvantage of the manual method of lubricating chain drive is ________.

Answers

Following are the disadvantages of manual lubrication:

Manual lubrication of chain drives requires safe maintenance and environmental regulations.Manual lubrication does not guarantee an optimal lubrication at the specific location.There remains a risk for the chances of negative productivity and increasing costs.Many machines are difficult to lubricate when in use.Excess lubrication can lead to damage and excess heat formationUnder lubrication can cause higher energy usage and damage to bearings.

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The data given to the right includes data from candies, and of them are red. The company that makes the candy claims that % of its candies are red. Use the sample data to construct a % confidence interval estimate of the percentage of red candies. What do you conclude about the claim of %? How many lines of symmetry does a regular pentagon have?44556677 What is the value of b? The main difference between europe and the united states regarding employee privacy is the u. s. weighs the value of privacy against other concerns and europe values human dignity.a. trueb. false Select the correct answer from the drop-down menu. anne applies a force on a toy car and makes it move forward. what can be said about the forces acting on the toy car at the moment anne applies the force? the forces acting on the toy car are . When you are working outside in the 90-degree heat and are so thirsty that you take a drink from the garden hose, you are responding to a ________ drive, according to the drive-reduction theory. A member of congress who votes for a bill with which he or she disagrees because a majority of his or her constituents favor it is acting as a:____. Political papers that generally pushed the plan of a particular political group and was subsidized by that political group were known as? In a field, there are some sheep and some goats. The ratio of sheep to goats is 3:1. If thereare 3 goats, how many sheep are there. What tool provides the basic software structure for communication on the internet? PLEASE HELP IM STUCK ON THIS In buchwald v. paramount, because the agreement between buchwald and paramount did not define certain terms, the court determined:________ How do you feel about what big data? What are the advantages and disadvantages? How has this new knowledge impacted how you use the internet and internet-connected tools? Geometry: fill in the blanks (ASAP!! Its urgent) Using the following table determine the probability a person tests positive who does not actually have Tuberculosis. What is the initiating event that eventually leads to cellular death during the shock syndrome? A total lunar eclipse occurs when:The Sun, Earth, and Moon are not aligned, but all direct sunlight is still blocked from the Moon.The Sun, Earth, and Moon are perfectly aligned, and no direct sunlight reaches the Moon.A portion of the Moon is darkened by a shadow cast by Earth.The Sun, Earth, and Moon are perfectly aligned, and the Moon is illuminated by the Sun. Jane is a manager who is self-absorbed and has a constant need for power and admiration. this is an example of a ________ leader. Which phrase best states the meaning of "pluck at his beard" as used in the excerpt?(8) ...Had King Solomon been the janitor, with all his treasures piled up in the basement, Jim would have pulled out his watch every time he passed, just to see him pluck at his beard from envyA. to be amusedB. to be annoyedC. to be approvingD. to be accepting Add 77 -10 with its additive inverse.